New paper published in Advanced Functional Materials!

New paper published in Advanced Functional Materials!

Here we use a bottom-up tissue engineering strategy to assemble cell-seeded 3D printed hydrogel modules with perfusable channel networks.

This work was led by Zachary J. Geffert, PhD and Daniel Fougnier, with key contributions from Bo Van Durme, Jenna Grutzmacher, Ryan Clarke, Suzie Cao, Zhenghao Li, Ujjwal Aryal, Jason Horton, and Sandra. Van Vlierberghe.

We are grateful for funding from National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), NDSEG Fellowship Program, Research Foundation – Flanders, FWO and F.R.S.-FNRS under the Excellence of Science (EOS) program. We are also thankful for support from Syracuse University, Syracuse University College of Engineering and Computer Science, and BioInspired Institute for Material and Living Systems.

If successful, this work will serve as a first step in assembling larger, complex constructs and mimic native organ structures while overcoming the nutrient diffusion limits of large tissue grafts.

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